During the American Civil War, the 46th Regiment, Georgia Volunteer Infantry engaged in the following campaigns and battles:
| Vicksburg Campaign, Mississippi | May 1863 | Jul 1863 |
| Jackson, Mississippi | 14 May 1863 | |
| Jackson Siege, Mississippi | 11 Jul 1863 | |
| Chattanooga Siege, Tennessee | Sep 1863 | Nov 1863 |
| Chickamauga, Georgia | 19 Sep 1863 | 20 Sep 1863 |
| Chattanooga, Tennessee | 23 Nov 1863 | 25 Nov 1863 |
| Atlanta Campaign, Georgia | May 1864 | Sep 1864 |
| Calhoun, Georgia | 5 May 1864 | |
| New Hope Church, Georgia | 25 May 1864 | 4 Jun 1864 |
| Pine Hill, Georgia | 15 Jun 1864 | |
| Dalton, Georgia | 25 Jun 1864 | 27 Jun 1864 |
| Kennesaw Mountain, Georgia | 27 Jun 1864 | |
| Atlanta Siege, Georgia | Jul 1864 | Sep 1864 |
| Smyrna Campground, Georgia | 4 Jul 1864 | |
| Chattahoochee River, Georgia | 5 Jul 1864 | 17 Jul 1864 |
| Peachtree Creek, Georgia | 20 Jul 1864 | |
| Atlanta, Georgia | 22 Jul 1864 | |
| Jonesboro, Georgia | 31 Aug 1864 | 1 Sep 1864 |
| Franklin, Tennessee | 30 Nov 1864 | |
| Nashville, Tennessee | 15 Dec 1864 | 16 Dec 1864 |
| Carolinas Campaign | Feb 1864 | 30 Apr 1865 |